It has been established, through rather painstaking processes over a period of several years, that primary constituents of the growth form are comprised of both iron and amino acids. The methods to achieve this have been described in detail on previous reports. The essence of impact to health has also been discussed at length, namely, that if these elements are used by the organism for its own growth then those same nutrients are being denied to the human host that supports the invasive growth. Your iron is at the core of your respiration and hence of all energy transfer within your body; proteins are the structural framework that allows your body to exist and grow. The absconding of both iron and amino acids (i.e., proteins) from the human body is by itself of sufficient damage to warrant a full and dedicated allocation of resources to this problem; this has not happened to date. This information has, however, been very useful to develop an entire host of strategies to mitigate this damage and these have been discussed on this site. There remains much to do.
This paper seeks to identify a host of organic compounds that are likely to comprise the core physical structure of biologically produced filaments characteristic of the Morgellons condition. A biological oral filament sample will be analyzed for the presence of candidate organic functional groups using the methods of infrared spectrophotometry. Potential health impacts from these same core structures are examined and compared to the observed , reported and documented symptoms (in part) of this same condition. Potential mitigating strategies, from a research perspective only, are discussed. A body of evidence, accumulated over a period of several years, reveals that the Morgellons condition is likely characterized by a host of serious physiological and metabolic imbalances. These imbalances are caused by the disruption of a variety of major body processes including, as a minimum, the regulation of metabolism by the thyroid, potential liver enlargement, a decrease of oxygen in the circulatory system, the utilization of amino acids important to the body, the oxidation of iron and a potential impact to neural pathways. The impact of this degradation to human health can be concluded to be serious, debilitating and potentially lethal in the cumulative sense; the reports of those who suffer from the condition are in alignment with these conclusions. This paper will summarize the body of work and chronology which leads to this more comprehensive hypothesis.
A maximum magnification that combines optical and digital means has recently been achieved. The development allows, under suitable conditions and sampling, a magnification of images at a reasonable resolution up to a level of approximately 18,000 power. This method has been applied to the examination of human blood samples as they relate to the “Morgellon’s” condition. A brief introduction to the results of this recent advance in microscopy that uses relatively limited means and equipment is presented below. Relevant topics of research that arise from the study include the more detailed appearance of the bacterial-like structure that has been studied extensively by this research. The degradation of the red blood cell exterior membrane is also clearly apparent. The rather striking appearance of white blood cells, their behavior with respect to the bacterial-like component, and the internal structures that are visible within the white blood cells are of high interest. The importance of an active immune system against the bacterial-like encroachment is immediately obvious. Introductory live-blood video analysis recently performed further emphasizes the importance of the relationship of the immune system to the Morgellon’s condition. This level of awareness and visibility on the Morgellon’s condition is a direct result of these recent advances in microscopy methods and techniques. The availability of more advanced equipment, should it become available, will accelerate this discovery process.
Under current projections, it will be some months ahead before I will be able to engage fully into the Environmental Filament Project that has been outlined under this site. In the interim, however, an important introduction to what lies ahead can be presented. Carnicom Institute is now able to display a series of scanning electron microphotographs of a typical sample; they will not be discussed in any detail until I am able to begin the study project. Those familiar with my work may be aware of my reluctance to use the term nano-technology in association with any environmental or biological samples examined thus far; this has been due to the lack of any electron microscope images that are derived directly from these same samples. This is no longer the case, and the use of the nano-technology term in association with this material is now fully justified. The samples shown below are identical to those that the United States Environmental Protection Agency has refused to identify or analyze. It has taken close to a decade and a half to acquire these images; appreciation is extended to all parties that have helped to make this information available to the public. Sufficient additional samples have been received, both national and internationally, to support the Institute project plans. This study will begin as the opportunity affords itself and as parallel work that is underway is completed. Light microscope images of the same material are also shown below.
An elderly, but wonderfully functional, Perkin Elmer 1320 infrared (IR) spectrophotometer has been acquired by the Carnicom Institute. This class of instrument has been sought after for many years by this researcher and organization. The value and purpose of an infrared spectrophotometer (along with other instruments as well) is that it can be used to gain insight into the molecular structure of organic compounds. This is a crucial need that has remained unfulfilled for many years in the biochemistry research that has taken place thus far. It is not an overstatement to realize that years of work can equivalently be accomplished with greater certainty and insight in relative moments of time with the proper instrumentation and resources. It is hoped that this equipment can be augmented or replaced with modern computer-based instrumentation at some point in the near future, however, the process of discovery at this important level can now begin.
Three methods that appear to interfere with the molecular bonding of the iron-dipeptide complex that is now understood to be characteristic of the "Morgellons" growth structure have been established and identified. The iron-protein complex is believed to be of, or similar to, the "Rieske Protein" (iron-sulfur) form. These three methods also appear to be variably successful in reducing the oxidation state of the encapsulated iron from the Fe(III) state to the Fe(II) state. The discovered methods involve the use of ascorbic acid (Vitamin C), N-acetyl cysteine (NAC) and glutathione. The results of applying glutathione appear to be especially promising at this time, as it appears that a major disruption in the bond structure has taken place after approximately 72 hours. The methods have been established and verified through visual, chemical and spectroscopic methods and each has an effect independent of the others. The hypothesis to be made here is that the growth of the organism itself may be interfered with as a result of this work.
The existence of certain amino acids, namely cysteine and histidine, as a dominant aspect of the "Morgellons" growth structure, appears to have been verified. This finding, along with that previously recorded on the important role that iron plays from a compositional standpoint, may be a highly important window into the structural framework of the Morgellons condition. It will also be found that deficiencies or disturbances of these particular amino acids correlate highly with symptoms that appear to frequently coexist with the condition, i.e., high oxidation levels and joint pains within the body.
The Carnicom Institute is embarking on a first of its kind study of the Morgellons condition often referred to as Morgellons Disease. The project will start with a questionnaire process, and this is in progress at this time. Subsequent developments of data collection and/or clinical studies may develop in the future depending upon support and resources.
A proteinaceous complex that derives from oral filament cultures has been identified. This finding, along with the significant presence of iron within the same culture growths, is paramount in the understanding of the physical nature of the filaments characteristic of the condition.
Clifford Carnicom summarizes the findings on Morgellons and outlines eleven different aspects of the phenomenon that is worth further investigation.
Substantial evidence exists which proves not only the existence and presence of the "Morgellons" pathogen, but also how this organism uses iron from our blood for its proliferation and growth. This pathogen changes the iron in our blood from its ferrous form (Fe2+) to a ferric form(Fe3+). This change has a direct, negative impact on human health. The iron in human blood must be in the ferrous form in order for it to bind to the oxygen molecule. If our blood is not in this state then it will not bind to the oxygen molecule and human health will suffer. Proposed mitigation strategies are discussed.
Analysis shows that the primary organism (or pathogen) characteristic of the "Morgellons" condition, as isolated and identified by Clifford Carnicom, causes a significant biochemical change in the nature of human blood in which it resides. The dramatic change in the character of the blood has been presented through visible observation for several years, but this change is now objectively and directly measurable through the use of spectral analysis, and these changes are graphed and discussed in this paper. This change in the general character of human blood, as it has been measured from several individuals, is regarded as highly significant and expressive of a potential fundamental change in the human condition. Normal hemoglobin is analyzed under a spectrophotometer, and then graphed with different levels of concentrations of the organism. All matter reacts in a unique fashion to electromagnetic energy which, in this case, is visible light. Hemoglobin, (the primary protein in human blood cells), has such a unique and characteristic spectrum over the visible light range, and witnessing such dramatic alterations of the blood from this organism as compared to unaltered hemoglobin in these graphs give a sense of urgency for not only further research in this area, but also to alert more people to what is going on and to inspire action to be taken to get these organisms located and stopped.